Posts Tagged ‘scientific health developments’

Parkinson’s disease and stem cells

Wednesday, March 9th, 2011

At AllClear we like to keep you up to date with the latest health developments, and this is a very interesting story. A genetic form of Parkinson’s disease has been created in the laboratory, a development which could eventually lead to new therapies, according to this article in the Times.

Scientists in the United States have successfully grown nerve cells, from the skin of a woman with Parkinson’s, that show several features of the disease. These will provide a valuable resource for studying how the degenerative brain condition progresses, and for testing candidate drugs.

So how did they create the disease artificially in the laboratory? Well the team first took skin cells from a woman with Parkinson’s disease. These cells were  then manipulated using a technique that reprogrammes adult cells so they are basically ‘blanked’, making them like embyonic stem cells. These cells, known as induced pluripotent stem (IPS) cells, then have the ability to form any tissue type in the body.

The IPS cells, bearing the Parkinson patient’s genetic code were coaxed to develop into nerve cells. At first, these cells appeared normal, but after 30 to 60 days they began to show characteristics typical of Parkinson’s.

So some really interesting research here, and yet another use for stem cells, that could potentially lead to treatments for Parkinson’s disease…

Train your brain – even on holiday!

Wednesday, May 5th, 2010

We all have heard of one way or the other how to train your brain – whether it is completing a Sudoku every day, Mensa puzzles, the brain training game on the Nintendo DS, or simply learning a new skill. But these activities don’t always fit that well with a holiday lazing on the beach or by the pool.

How can you train your brain when relaxing on the beach?

How can you train your brain when relaxing on the beach?

Nevertheless, according to an article in the Daily Mail on the 25th April, the ability of the brain to cope with life’s stressful events, and respond to injuries, all relates to how we have treated our brain in the past. When we deplete our brain reserve – the extra neurons we have to deal with unexpected events – we become more vulnerable. Therefore, to keep our brain strong, we should be trying to train our brain as much as possible. And at the same time, we should try to avoid the activities that are known to deplete brain reserve. These include:

  • Excessive alcohol
  • Poor diet
  • Stress
  • Lack of sleep
  • Excessive caffeine
  • Lack of exercise

So all the usual suspects then. But a holiday can be an ideal opportunity to recharge your batteries and help your brain out! When you go on holiday, you might want to think about what other opportunities you can use to train your brain. Whether it is taking a puzzle book with you to do on the plane, or taking a language book with you rather than the normal paperback? Or visiting new places and learning new skills.

And what is the best thing you could do for your brain? Table tennis, apparently. This is because your hands, eyes and feet are all working together while you are thinking about the ball. It is aerobic chess. So when you see that abandoned table tennis table in the hotel grounds, or on board ship – why not give it a go?!

Reading for health

Tuesday, February 23rd, 2010

Just a quick health story about treatment for stroke victims – really nice to include in our blog as it is such a positive story.

 It is from  an article about InterAct, a reading service charity, where professional actors read aloud to stroke patients at hospital. A number of patients have said that this provides an invaluable service, which relay aids in their recovery.

Being read to after a stroke can improve your health

Being read to after a stroke can improve your health

 In Britain, the depression rate among stroke sufferers is almost 70% and according to Dr Lalit Kalra, Professor of Stroke Medicine at London’s King College Hospital, depression can greatly care the healing process. This is where InterAct comes in, there is evidence that stimulation of the brain speeds up recovery in stroke victims.

 The charity was the brainchild of theatre director Caroline Smith, and was launched in 2000 as a way for the arts and the health service to collaborate. Caroline was conscious of the abundance of wasted talent among the hundreds of ‘resting’ professional actors in Britain. Today, InterAct provides a regular reading service in more than 21 hospitals and 34 stroke clubs worldwide.  Listening to a person, instead of the radio, is important because the actor can interpret his audience of one, and adapt their reading to suit the person’s needs.

 I think this charity’s aims sound great. It is a way to help improve stroke patients wellbeing, while at the same time a fulfilling volunteer opportunity for out of work actors…What do others think?

You are only as old as you feel? Just how old are you really?

Tuesday, February 23rd, 2010

If you are in your later years in life, you might be forgiven for occasionally forgetting quite how old you are! But actually, your chronological age is not the full story anyway. It is when you look at the biological age of your individual organs that things start to get really interesting, according to this article.

It is possible to remain much younger than your birth age, in terms of your biological age, if you look after yourself. Equally, you can develop age related disease far younger than you otherwise would if you smoke, drink alcohol and eat unhealthy food, according to Dr Lipkin, Priory Hospital, Birmingham.

 So what can this mean for you?

What's your eye health?

What's your eye health?

 Eyes: People gradually lose the ability to focus close up, which is why those over 45 may need to wear reading glasses. An average 20 year old can focus on objects held 3inches from their eyes, a  average 45 year old can only focus on objects 8 inches away. So depending on how well your eyes can focus, that will determine what you eye ages is…

Liver: Unlike organs such as the lungs, the tissue of the liver can regenerate, meaning it can still be pretty healthy as you get older. However, you can age your liver if you really abuse it with excessive and long term drinking. A fibroscan can measure the damage of the liver, and how well it can regenerate, or whether the damage is permanent. A fibroscan at the London Clinic Liver Centre costs £230. If the level of fibrous tissue is low, your liver age is low.

Hearing: With age, cells in the inner ear that enable us to hear high-pitched sounds die. The result is hearing loss. This usually begins around age 55, but excessive exposure to loud noises for long periods can mean this loss occurs at a younger age.

 Heart: With age, factors such as higher blood sugar and higher levels of bad LDL cholesterol will raise your risk of cardiovascular diease, and vice versa. A heart health check at London Medical Chambers costs £100.

 Kidneys:  Smoking, diabetes and high blood pressure can all damage the kidneys, and so speed up their ageing process. Blood tests to assess kidney function are available through your GP.

Lungs: A spriometry test, which measures lung capacity, can determine your lung age. The test involved full inhalation and exhalation into a measuring device. The spirometer measures how springy your lungs are, you lose this with age, but it is also made worse by smoking.  Once you lose lung elasticity, you cannot get it back, but you can look after your lungs by not smoking and by keeping fit.

Ovaries: With age, the number of eggs, and the quality of those eggs, declines. Ovary size can also diminish with age, while the risk of other problems, such as ovarian cysts increases. All women are born with 1 to 2 million eggs but most of these waste away, and by puberty women only have about 300,000 left.  After 30, you may only have a few thousand eggs left. Blood tests can indicate levels of AMH, a hormone that indicates the number of eggs you have left. Smoking, alcohol and stress all significantly speed up your fertility loss. A fertility MOT at the Centre for Reproduction and Advanced Technology costs £200. 

 This gives a lot of stuff to think about, don’t you think? What do you think your biological age would be? Do you know?

First stem cells transplanted into spinal cord

Thursday, February 11th, 2010

Here at Globebloggers we aim to keep you up to date with the latest scientific research around specific medical conditions. This article in CNN is particularly fascinating. It tells how near the end of January, in Georgia, stem cells were directly injected into the spinal cord of a patient for the first time.

Doctors injected stem cells from 8-week-old fetal tissue into the spine of a man in his early 60s who has advanced ALS, amyotrophic lateral sclerosis. ALS is better known as Lou Gehrig’s disease, named after the New York Yankees’ first baseman who retired from baseball in the 1930s after being diagnosed with the disease. ALS is a fatal neurodegenerative disease that causes the deterioration of specific nerve cells in the brain and spinal cord called motor neurons, which control muscle movement. There is currently no cure for ALS, and patients usually die within two to five years of diagnosis. As the illness progresses, patients lose their ability to walk, talk and breathe.

 The stem cell injection is part of a clinical trial, by Neuralstem a Maryland-based biotech company, designed to determine whether it is safe to inject stem cells into the spinal cord and whether the cells themselves are safe. The company is fully funding the research and provides the stem cells that are being injected into the patients.  At least 12 patients are expected to participate in this early research. This first patient in the clinical trial received several injections of stem cells into the lumbar region of the spinal cord, the area that controls leg function, because most ALS patients first lose muscle function in their legs.

Karl John, Neuralstem’s Chief Scientific Officer explained that the approach is novel because they are injecting stem cells directly into the spine. John said that once the safety of this type of transplant is determined, he and his colleagues hope to see whether this is a possible treatment for ALS.