Posts Tagged ‘health news’

Parkinson’s disease and stem cells

Wednesday, March 9th, 2011

At AllClear we like to keep you up to date with the latest health developments, and this is a very interesting story. A genetic form of Parkinson’s disease has been created in the laboratory, a development which could eventually lead to new therapies, according to this article in the Times.

Scientists in the United States have successfully grown nerve cells, from the skin of a woman with Parkinson’s, that show several features of the disease. These will provide a valuable resource for studying how the degenerative brain condition progresses, and for testing candidate drugs.

So how did they create the disease artificially in the laboratory? Well the team first took skin cells from a woman with Parkinson’s disease. These cells were  then manipulated using a technique that reprogrammes adult cells so they are basically ‘blanked’, making them like embyonic stem cells. These cells, known as induced pluripotent stem (IPS) cells, then have the ability to form any tissue type in the body.

The IPS cells, bearing the Parkinson patient’s genetic code were coaxed to develop into nerve cells. At first, these cells appeared normal, but after 30 to 60 days they began to show characteristics typical of Parkinson’s.

So some really interesting research here, and yet another use for stem cells, that could potentially lead to treatments for Parkinson’s disease…

Medical Advances in 2011: Pneumatic Drills, new arthritis drugs, and detecting ‘soldier’ cancer cells

Wednesday, March 2nd, 2011

I read an interesting article all about medical advances in 2011, and I thought I would pick out a couple to share with you…

1.     Pneumatic drill that can clear blocked arteries: A tiny vibrating device that breaks up hard deposits in leg arteries. Blocked arteries in the legs, or peripheral arterial disease (PAD), affect one in five men and one in eight women aged over 50. It’s estimated that PAD results in 100 amputations a week in Britain, mostly in diabetics with poor blood circulation. The usual treatment is to insert a thin tube into the main artery in the thigh and feed through a wire to try to break through the blockage. But if the deposit has hardened, the wire often cannot penetrate, and patients face surgery or amputation. The tip of the wire on the new device vibrates 20,000 times a second. This punches a hole through the middle of the deposit, allowing doctors to inflate a tiny balloon to displace the blockage. Each procedure costs around £1,000 and the technology is being rolled out to NHS hospitals.

2.     New tablets for prostate cancer: For men with advanced prostate ­cancer, where the tumour has spread to other parts of the body, the only option is chemotherapy to slow the spread. However, this has toxic side-effects such as fatigue, nausea and hair loss. But a new tablet is due to be launched later this year that not only extends ­survival, but has fewer side-effects. Abiraterone, a once-a-day pill ­developed at the Institute of Cancer Research in London, has far milder side effects.  In tests on men whose cancer had stopped responding to all other treatments, the drug extended average survival from 10.9 months to 14.8 months.

3.     New anti-inflammatory arthritis drug: Non-steroidal ­anti-inflammatories, or NSAIDs, are one of the main treatments used in rheumatoid arthritis and ­osteoarthritis, which affect around 1.5 million people in Britain. The best known is aspirin. The problem is these tablets can be harsh on the stomach.  Patients are usually also prescribed another type of drug to stop stomach acid being produced (a proton pump inhibitor), but many forget or don’t bother to take it. Now a new drug that combats this problem is expected to become widely available in 2011. Called Vimovo, it was recently approved for use in Britain and combines an anti-inflammatory with a proton pump inhibitor, esomeprazole. When the new drug is swallowed, it first releases a dose of ­esomeprazole. Only when this has had time to stop the production of acid is the anti-inflammatory then released, several minutes later. It is likely to be given to patients who need higher doses of NSAIDs

4.     Early lung cancer predictor: A blood test that predicts lung cancer up to five years before symptoms emerge is due to launch in the next few months. It is expected to be followed by a range of similar blood tests that will be able to identify breast, ­ovarian, bowel and prostate cancer victims long before they fall ill. The test is based on the fact that as soon as cancer cells start to develop, and long before the patient notices any symptoms, the immune system starts to release antibodies, ‘soldier’ cells, that patrol the bloodstream trying to kill off malignant invaders. The new lung cancer test, which has already been launched in the U.S., measures levels of six ­specific antibodies known to be linked to lung cancer.

I will share more information on these developments as I hear more…

A 2011 Prescription

Wednesday, January 5th, 2011

Ok well it is the New Year, but a lot of people already seem to be gloomy – what with the financial state of the country, and the risk of more snow looming, to name just a few. That is why I decided to make this blog a bit more positive.

Follow these seven simple steps to better health. They might not be quite as difficult as you would think. There are plenty of less obvious, even counterintuitive, ways we can extend our lives and improve our health this year….

1.     Don’t diet too much: being slightly overweight is good for you

Until last year, the commonly accepted marker of a healthy weight-for-height was the BMI: your weight in kilograms divided by the square of your height in metres. BMI charts originally identified 20-25 as the target range for the lowest risk of future ill health: below 20 and you were too thin; above 25 and you were overweight; above 30 and you were obese.

 But that changed in 2010. It seems a higher BMI score, of 25-27.5, is at least as healthy in terms of cardiovascular risk as one of 20-22.5. You really don’t need to worry if you are a little overweight – provided you aren’t more than around 5kg from the ideal weight for your height. The new emphasis is on waist measurements: men should aim for less than 38 inches and women should aim for 34 inches or less.

2.     Exercise only in moderation

Helath tips 2011

Do excercise, but not too much!

BDNF (brain-derived neurotrophic factor)  was a buzz word for fitness researchers in 2010. BDNF stimulates the formation of new connections between brain cells.

Regular exercise increases levels of BDNF, so it should be good for you – but there’s a snag – too much exercise lowers BDNF levels. Does that have a damaging effect on brain cells? We don’t yet know, but anecdotal evidence of the breakdown in health of athletes who train to near-exhaustion every day tends to suggest that it does.

The main message, though, is to give your body time to recover after exercise. The current advice is to exercise to breathlessness for around 30 minutes, and avoid exercising more than three or four times a week.

3.     It’s not how much fruit and veg you eat, but which type

According to American, Chinese and Finnish studies, eating lots of green, leafy vegetables helps to prevent type-2 diabetes, even if you don’t lose weight in the process.

 However, the big finding for 2010 was that particular foods can lower the rates of specific diseases. For example, chives, leeks, shallots, onions and garlic are linked with much reduced rates of stomach and colon cancer, and it is claimed, in the Journal of the National Cancer Institute, that tomatoes help to protect against prostate cancer. It seems cooking tomatoes, especially in olive oil, or eating them in ketchup, is even more effective than eating them fresh. Best get shaking that ketchup bottle then!

4.     Get more light

One way to improve your brainpower may be simply to sit in bright light for a few hours each day. Research has found that people performed better in mental tests when under bright light. The brighter the light, the more effective it is (pale blue light is even better).

I find this one particularly interesting because I would always  rather sit or work in a  bright room, rather than a dull gloomy room. Never knew that I might have been expanding my brain at the same time!

5.     Throw away your vegetable peeler

health tips 2011

It is important to eat more of the skin, core and stem of fruit and veg

Now I don’t know about you, but I have heard before that it is better to eat the skins of fruit – full of fibre and other nutrient goodness.

But today’s buzzword is biosynergy, the theory that each part of a fruit or vegetable combines with the other parts to reinforce its nutritional benefit. Apparently we shouldn’t just be tucking into the skin of fruit and veg, but the  stalks and cores also protect against cancer and boost nutrition. Dr Marilyn Glenville, former president of the Food & Health Forum at the Royal Society of Medicine has listed the fruit that she would persuade us to eat whole. This includes bananas – the peel is high in serotonin, needed in the brain to lighten mood and ease depression – and kiwi fruits, whose skin is high in antioxidants and is claimed to have anti-inflammatory properties (golden kiwis have thinner, sweeter skins, so could be more acceptable eaten whole). She also advises eating the cores of pineapples, which contain twice the levels of bromelain, a digestive enzyme that protects the stomach lining, and orange and tangerine peel, which contain super-flavonoids that can improve your chances of avoiding a heart attack or stroke. Broccoli stalks contain more calcium, vitamin C and fibre than the florets too.

So how can we consume this food? I can’t say I could see myself tucking into banana or tangerine peel, the skin would be too chewy. Well, Glenville recommends adding grated citrus peel to your food or putting the whole, unpeeled fruit into a juicer. Garlic skin, for contains six separate antioxidant compounds, according to Japanese researchers. Glenville recommends roasting garlic whole, along with other Mediterranean vegetables. Well that doesn’t sound too bad and maybe a relatively easy Resolution for 2011!

6.     Limit your alcohol consumption

The news about health and alcohol isn’t so surprising. Generally, we are drinking far more than any previous generation, increasing problems of failing livers and brains. Not only do we drink much more, but what we drink contains much higher levels of alcohol. Beers are stronger, while the alcohol content of wines has risen from around 8% to around 13%, and we drink them in 250ml rather than 125ml glasses. So the message of drinking in moderation remains the same – and make sure you know what a unit is too

The idea that red wine has specific health advantages (because it contains the magic flavonoids) doesn’t really hold up, either. It is wiser to eat blueberries instead. According to recent research from Reading University, blueberries improve our attention levels and possibly our memories, too.

7.     Learn an instrument, at any age

For a long time, medical consensus was that our brains were fully developed by our late teens, and that we started to lose neurones after that point. If we did keep on learning from then on, we were using nerves and pathways that were already established: we couldn’t “grow” more neurones or connections. But according to the European Journal of Neuroscience, we may be able to train our brains to develop even once we are adults, even though it may be more difficult than in childhood. Research done with London taxi drivers provided evidence of new connections between the two halves of the brain after they learned “the Knowledge”.

 Professional musicians have the same new connections as did the taxi drivers. Brain scans show that many areas of the brain light up when we perform the simplest of tasks, and that musical training improves and widens these connections. So become proficient in any instrument and you should improve your dexterity, intellectual capacity and resistance to age-related dementia. Hmm possibly another good new Year’s resolution to add to the list – I have always wanted to learn how to play the piano properly….

The full details of these 7 health tips for 2011 can be found in the Guardian, dated 1st January here

To vaccinate or not to vaccinate

Tuesday, November 9th, 2010

So your exotic holiday is all booked, you have paid the deposit and you are ready to go. But wait a minute, don’t you need vaccinations for your holiday?

 Yes, it can be a bit of a pain organising your injections beAllClear Travel vaccination Appfore your holiday, but there is now a new app that does most of the hard work for you. All you need to do is detail your destination and then the app lists all the vaccinations that you might ever need. The vaccinations are listed in a traffic light system with red being recommended, yellow being sometimes recommended and with orange, the requirement for vaccination varies. Remember to also check how long before your holiday you require any jabs. I’m afraid that you actually then need to go and have the injections yourself though! Still, the app is a really quick and easy way to help you get all prepared for your holiday.

The App is created by AllClear Travel, a specialist travel insurance provider, and you can book your travel insurance using the app at the same time if you like, or speak to an AllClear advisor on a live webchat if you have any questions.

 You can  download the app here, and best of all it is completely FREE! Let us know what you think of it below.

Simon Cowell speaks out about cancer

Tuesday, July 13th, 2010

Here at Globebloggers we have spoken many times about travelling with cancer. That is why we just wanted to share this article we found  in the Daily Mail to share the experiences of someone you may know (he is just a little bit famous) and his experiences of cancer. I am talking about Simon Cowell, of ‘Britain’s Got Talent’ and ‘X-Factor Fame.

Whether you like Simon Cowell or not as a celebrity, he is now involved with a charity promoting a very worthy cause since Julia, his mother, suffered from breast cancer 12 years ago. Julie is honorary president of Against Breast Cancer and Simon is a patron. Against Breast Cancer is a UK charity working with a research team at University College London to find a breast cancer vaccine.

Simon’s mother has continued to live a very full life since her breast cancer, while making sure she has regular checkups, and apparently Simon is now taking his health more seriously too. Julia says her son has even ditched dairy products and greasy food in favour of fruit, and plans to quit smoking by the time he is 50. He currently smokes 15 cigarettes a day.

If you suffer from cancer, or are undergoing treatment, it is important, like Julia to still be able to do the things you enjoy as much as possible, and that includes holidays. We can provide more information about travelling with cancer here. Please let us know if there is anything more that you would like to find out that we can help with.

Menacing Migraines

Tuesday, May 25th, 2010

When it comes to migraines everyone is different – for people who are affected their triggers and their possible cures are often varied. It’s interesting that although the migraine has been known of for centuries, an Egyptian medical scroll dated 1500 to 3000BC is the first known mention of a migraine, they are not actually very well understood. This can be especially annoying when the migraine impacts on your  daily life. It may mean lots of days off work, or that you spend your whole holiday worrying about getting a migraine, and missing out on holiday activities.

According to this article in the Daily Mail, the single biggest misunderstanding is that a migraine is just a severe headache. It is, in fact, a complex neurological disease that affects the central nervous system. Migraines are caused by abnormal brain biochemistry and are not, as some believe, self-induced. They are a chronic illness that is present from birth and 70-80% of sufferers have a family history of the condition.

One in ten Britons suffer from migraines – one in five women and one in 20 men. Migraine is the ninth leading cause of disability in the world – more common than diabetes or asthma.

There’s a widespread myth that people who suffer from migraine should avoid chocolate and foods with the flavour enhancer, Mono Sodium Glutamate. Actually, these things can trigger a migraine in some migraine sufferers, but not in everyone. As every migraine is different, finding out what triggers an attack, and how to control and manage it, is the key to understanding this debilitating condition. Triggers can be anything from a glass of red wine, to a change in the weather, to lack of sleep or the smell of strong perfume. Unfortunately, all things that could affect you when you are on holiday and just want to relax and enjoy your time away.

Migraine vs normal headache
A headache is a pain in the head that occurs randomly and sporadically but is not actually a disease
 People who suffer from headaches don’t tend to remember the specific details of the experience in the way that migraine sufferers do.
Rather than the dull pain of a tension headache, 85% of migraine sufferers experience a continual throbbing, pulsating or pounding pain
A Migraine almost never consists of head pain alone – other symptoms include nausea and vomiting, sensitivity to light or sound, tingling or strange sensations in the skin, to visual changes, hunger pangs, slurred speech, excessive weeping, and bloodshot eyes

Cures

As we have said, migraine is a unique illness, so the treatments vary widely too.

Interestingly, some say the best cure for migraines can be a cup of coffee or a caffeinated soft drink.  This is because caffeine constricts blood vessels which can decrease pain. Caffeine can be so effective that many over-the-counter migraine medications include it as an ingredient, including Anadin Extra.

Another good possible remedy is massage. Tight muscles or muscles in spasm can be a migraine trigger for many people. You might have a tight neck, back or shoulders, especially if you sit in front of a computer or drive for hours each day. You may have tight facial or scalp muscles, or clench your teeth, especially at night, so that you wake up with a migraine.

A more physical potential remedy is yoga. Desperate Housewives actress Marcia Cross uses Yoga to help treat her Migraine. Her method is backed up by a recent study in India which found that migraine sufferers who used yoga in combination with meditation and other relaxation techniques had fewer migraines with less pain. Anxiety and depression were also significantly reduced.

The final remedy brings me back to that magical magnesium.   Although it does not help everyone, taking a daily supplement may help prevent migraines. As I have said in a previous blog, magnesium is a mineral that regulates how your blood vessels operate, reduces pain and calms your nervous system, which is probably why it helps with migraines.  It can also help decrease stress and it helps regulate blood-sugar levels  -  two common migraine triggers.  Many people are deficient in magnesium in part because the high fat and high sugar in the Western diet block its absorption into the body.  Often those who suffer migraines have lower magnesium levels than normal.  Talk to your GP first to see if there is any reason why you should not take it, such as kidney problems.

If you suffer from migraines, and have a holiday booked, you might want to look at www.allclear4you which is all about travelling with medical conditions.

Statins – the pros and cons

Tuesday, May 11th, 2010

Statins, the cholesterol lowering tablets, are prescribed to around 6 million people in the UK, so it is likely that some of you reading this blog are currently taking statins. Statins work by reducing the amount of ‘bad cholesterol’ in the blood, which can cause the build up of fatty deposits in the arteries and lead to coronary artery disease. Statins affect the amount of cholesterol that your cells make, forcing them instead to gather cholesterol from your bloodstream, thereby reducing your blood cholesterol level. They have been hailed as a wonder drug in fighting heart disease, and the British Heart Foundation credits statins with saving 10,000 lives a year. However, potential side effects include sleep disturbance, depression and memory problems.

Here are some of the arguments ‘For’ and ‘Against’. For the full detail of these arguments, check out this article :

For

  • Statins save lives by preventing heart attacks and strokes by delaying the onset of cardiovascular disease (which is Britain’s biggest killer, responsible for 1 in 3 deaths)
  • Serious problems such as muscle wasting are very rare. Many people take statins without any problems
  • It is always preferable to  alter your lifestyle to lower risk – cutting out fatty foods, quitting smoking, losing weight, and exercising more. But such measures are not always enough to combat rising cholesterol.

Against

  • Side effects include muscle problems, hair loss, depression and impotence
  • People sometimes think that taking statins then give them licence to eat what they like
  • Patients can be motivated by panic to take statins because they fear that they are at risk if they don’t

 If you do take statin medication, and have a holiday planned, you may want to check out our AllClear4you which contains lots of useful information about travelling with medication, and any special considerations you might need.

Gym Tots

Thursday, May 6th, 2010

I found an interesting story about baby health, which I wanted to share with you.

This new research shows that babies whose mothers do aerobic exercise during pregnancy may have healthier hearts! The researchers believe that ‘womb workouts’ have health benefits that continue into adulthood, lowering the risk of heart disease, stroke, diabetes and hypertension. The reasoning is that the heart is a muscle which, like other muscles, becomes stronger through conditioning. And if it is stronger, the heart puts less effort into pumping the same amount of blood.

Now obviously we always talk on this blog and on www.allclear4you.co.uk about ways to live a healthier lifestyle, but it is incredible to think that ways to improve your cardiovascular health can start before you are even born! I mean we are aware of the dangers of smoking and drinking alcohol while you are pregnant for the unborn baby, but benefits of exercise for the baby (not just the mother) is a new area. heart_stethoscope

This research was based on 60 healthy pregnant women, aged 21-35. Half the women exercised and half did not. Exactly how maternal exercise shapes the foetal heart is not clear. One theory is that the development of the foetus nervous system is boosted by exposure to maternal hormones released during exercise.

But whatever the mechanism, it is fascinating to think that preventative medicine could start in the womb. Something to think about…

Train your brain – even on holiday!

Wednesday, May 5th, 2010

We all have heard of one way or the other how to train your brain – whether it is completing a Sudoku every day, Mensa puzzles, the brain training game on the Nintendo DS, or simply learning a new skill. But these activities don’t always fit that well with a holiday lazing on the beach or by the pool.

How can you train your brain when relaxing on the beach?

How can you train your brain when relaxing on the beach?

Nevertheless, according to an article in the Daily Mail on the 25th April, the ability of the brain to cope with life’s stressful events, and respond to injuries, all relates to how we have treated our brain in the past. When we deplete our brain reserve – the extra neurons we have to deal with unexpected events – we become more vulnerable. Therefore, to keep our brain strong, we should be trying to train our brain as much as possible. And at the same time, we should try to avoid the activities that are known to deplete brain reserve. These include:

  • Excessive alcohol
  • Poor diet
  • Stress
  • Lack of sleep
  • Excessive caffeine
  • Lack of exercise

So all the usual suspects then. But a holiday can be an ideal opportunity to recharge your batteries and help your brain out! When you go on holiday, you might want to think about what other opportunities you can use to train your brain. Whether it is taking a puzzle book with you to do on the plane, or taking a language book with you rather than the normal paperback? Or visiting new places and learning new skills.

And what is the best thing you could do for your brain? Table tennis, apparently. This is because your hands, eyes and feet are all working together while you are thinking about the ball. It is aerobic chess. So when you see that abandoned table tennis table in the hotel grounds, or on board ship – why not give it a go?!

Got a good tan on your holiday?

Wednesday, March 31st, 2010

In the UK, considering the appalling weather that we often experience, a big reason for going on holiday is often to get that elusive tan.  We come home from our beach holiday, relaxed and refreshed, proud to show off our tan and hear the cries of ‘You look well’ from others left languishing in the office!

We all may try to get a tan on holiday, but what if you have this tan all year round

We all may try to get a tan on holiday, but what if you have this tan all year round

 But if you go brown, even when you have not even been in the sun, you could not be well at all. Genetic haemochromatosis  - also known as primary iron overload – is a condition that causes the body to retain too much iron from the diet.

Iron is a mineral vital to the human body, regulating cell growth and ensuring oxygen flows to the cells, keeping immunity and energy levels high. But like so many things in the body, there is a balance, and too much iron can be toxic. A build up of iron in the brain’s pituitary gland can trigger a classic symptom that gives rise to the conditions other name – bronze diabetes. This is because it can appear as though you have a permanent tan. The reason is that iron overload in the pituitary gland stimulates  an over production of melanin, the pigment that gives our skin its colour.

Undiagnosed iron overload can cause a wide range of health issues, including diabetes, heart disorders, chest and joint pain, liver cirrhosis, pancreatic problems and cancer. A build up of iron in the bones can lead to crystallisation.

It is a common genetic condition. Two genes have been identified that cause it and about 1 in 5000 people in the UK are affected. It is prevalent in all Caucasian populations, but may be slightly higher in those of Irish descent.

The good news is that this disorder is a treatable condition. However, the problem is that because you may look well, the condition can be undiagnosed for years. If you have any of the symptoms, or are getting browner even when you haven’t been on holiday, then just ask your doctor for a simple blood test which can check your iron levels.

 The treatment is very simple – giving blood, as two thirds of the body’s iron lie in the blood. Patients generally give a pint a week until their levels return to normal, and then once every 3 to 6 months. The blood is safe to be used by blood banks,  since people without the faulty gene can rid themselves of the excess iron.

I had heard of this disease before, but didn’t realise that a symptom is a permanent tan. I will think twice before being jealous of people with a year long tan…